From: [di 015] at [cleveland.Freenet.Edu] (Jim Collingwood)
Newsgroups: alt.drugs
Subject: nitrous: msds
Date: 6 Jul 1993 18:39:24 GMT
OHS16790 PAGE 001 OF 007
MATERIAL SAFETY DATA SHEET
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OCCUPATIONAL HEALTH SERVICES, INC. FOR EMERGENCY SOURCE INFORMATION
11 WEST 42ND STREET, 12TH FLOOR CONTACT: 1-615-366-2000
NEW YORK, NEW YORK 10036
1-800-445-MSDS (1-800-445-6737) OR
1-212-789-3535
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SUBSTANCE IDENTIFICATION
CAS NUMBER: 10024-97-2
RTECS NUMBER: QX1350000
SUBSTANCE: NITROUS OXIDE
TRADE NAMES/SYNONYMS:
DINITROGEN MONOXIDE; FACTITIOUS AIR; LAUGHING GAS;
HYPONITROUS ACID ANHYDRIDE; NITROGEN (I) OXIDE; NITROGEN OXIDE;
STCC 4904340; UN 1070; NITROGEN OXIDE (N2O); DINITROGEN OXIDE;
NITROUS OXIDE, COMPRESSED; N2O; OHS16790
CHEMICAL FAMILY:
INORGANIC GAS
MOLECULAR FORMULA: N2-O
MOLECULAR WEIGHT: 44.01
CERCLA RATINGS (SCALE 0-3): HEALTH=2 FIRE=0 REACTIVITY=0 PERSISTENCE=0
NFPA RATINGS (SCALE 0-4): HEALTH=U FIRE=0 REACTIVITY=0
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COMPONENTS AND CONTAMINANTS
COMPONENT: NITROUS OXIDE PERCENT: 100.0
CAS# 10024-97-2
OTHER CONTAMINANTS: NONE
EXPOSURE LIMITS:
NITROUS OXIDE:
50 PPM (90 MG/M3) ACGIH TWA
25 PPM NIOSH RECOMMENDED TWA
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PHYSICAL DATA
DESCRIPTION: COLORLESS GAS OR LIQUID WITH A SLIGHTLY SWEET ODOR AND TASTE.
BOILING POINT: -128 F (-89 C) MELTING POINT: -132 F (-91 C)
SPECIFIC GRAVITY: 1.8122 G/L @ 25 C VAPOR PRESSURE: 760 MMHG @ -88 C
SOLUBILITY IN WATER: 59% AT 25 C VAPOR DENSITY: 1.530
SOLVENT SOLUBILITY: SOLUBLE IN SULFURIC ACID, ALCOHOL, ALKALINE SOLUTIONS,
ETHER AND OILS.
VISCOSITY: 0.0145 CPS @ 25 C
OHS16790 PAGE 002 OF 007
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FIRE AND EXPLOSION DATA
FIRE AND EXPLOSION HAZARD:
NEGLIGIBLE FIRE HAZARD WHEN EXPOSED TO HEAT OR FLAME.
CYLINDER MAY EXPLODE IN HEAT OF FIRE.
GAS-AIR MIXTURES ARE EXPLOSIVE.
OXIDIZER: OXIDIZERS DECOMPOSE, ESPECIALLY WHEN HEATED, TO YIELD OXYGEN OR
OTHER GASES WHICH WILL INCREASE THE BURNING RATE OF COMBUSTIBLE MATTER.
CONTACT WITH EASILY OXIDIZABLE, ORGANIC, OR OTHER COMBUSTIBLE MATERIALS
MAY RESULT IN IGNITION, VIOLENT COMBUSTION OR EXPLOSION.
FIREFIGHTING MEDIA:
DRY CHEMICAL OR CARBON DIOXIDE
(1990 EMERGENCY RESPONSE GUIDEBOOK, DOT P 5800.5).
FOR LARGER FIRES, USE WATER SPRAY, FOG OR REGULAR FOAM
(1990 EMERGENCY RESPONSE GUIDEBOOK, DOT P 5800.5).
FIREFIGHTING:
MOVE CONTAINER FROM FIRE AREA IF YOU CAN DO IT WITHOUT RISK. APPLY COOLING
WATER TO SIDES OF CONTAINERS THAT ARE EXPOSED TO FLAMES UNTIL WELL AFTER FIRE
IS OUT. STAY AWAY FROM ENDS OF TANKS. FOR MASSIVE FIRE IN CARGO AREA, USE
UNMANNED HOSE HOLDER OR MONITER NOZZLES; IF THIS IS IMPOSSIBLE, WITHDRAW FROM
AREA AND LET FIRE BURN (1990 EMERGENCY RESPONSE GUIDEBOOK, DOT P 5800.5, GUIDE
PAGE 14).
EXTINGUISH USING AGENTS SUITABLE FOR TYPE OF SURROUNDING FIRE. COOL CONTAINERS
WITH FLOODING AMOUNTS OF WATER, APPLY FROM AS FAR A DISTANCE AS POSSIBLE.
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TRANSPORTATION DATA
DEPARTMENT OF TRANSPORTATION HAZARD CLASSIFICATION 49-CFR 172.101:
NONFLAMMABLE GAS
DEPARTMENT OF TRANSPORTATION LABELING REQUIREMENTS 49-CFR 172.101 AND
SUBPART E:
NONFLAMMABLE GAS
DEPARTMENT OF TRANSPORTATION PACKAGING REQUIREMENTS: 49-CFR 173.304
EXCEPTIONS: 49-CFR 173.306
FINAL RULE ON HAZARDOUS MATERIALS REGULATIONS (HMR, 49 CFR PARTS 171-180),
DOCKET NUMBERS HM-181, HM-181A, HM-181B, HM-181C, HM-181D AND HM-204.
EFFECTIVE DATE OCTOBER 1, 1991. HOWEVER, COMPLIANCE WITH THE REGULATIONS IS
AUTHORIZED ON AND AFTER JANUARY 1, 1991. (55 FR 52402, 12/21/90)
EXCEPT FOR EXPLOSIVES, INHALATION HAZARDS, AND INFECTIOUS SUBSTANCES, THE
EFFECTIVE DATE FOR HAZARD COMMUNICATION REQUIREMENTS IS EXTENDED TO
OCTOBER 1, 1993. (56 FR 47158, 09/18/91)
OHS16790 PAGE 003 OF 007
U.S. DEPARTMENT OF TRANSPORTATION SHIPPING NAME-ID NUMBER, 49 CFR 172.101:
NITROUS OXIDE, COMPRESSED-UN 1070
U.S. DEPARTMENT OF TRANSPORTATION HAZARD CLASS OR DIVISION, 49 CFR 172.101:
1.1 - EXPLOSIVES (WITH A MASS EXPLOSION HAZARD)
U.S. DEPARTMENT OF TRANSPORTATION LABELING REQUIREMENTS, 49 CFR 172.101
AND SUBPART E:
NONFLAMMABLE GAS
U.S. DEPARTMENT OF TRANSPORTATION PACKAGING AUTHORIZATIONS:
EXCEPTIONS: NONE
NON-BULK PACKAGING: 49 CFR 173.304
BULK PACKAGING: 49 CFR 173.314 AND 49 CFR 173.315
U.S. DEPARTMENT OF TRANSPORTATION QUANTITY LIMITATIONS 49 CFR 172.101:
PASSENGER AIRCRAFT OR RAILCAR: 75 KG
CARGO AIRCRAFT ONLY: 150 KG
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TOXICITY
NITROUS OXIDE:
TOXICITY DATA: 24 MG/KG/2 HOURS INHALATION-HUMAN TDLO; MUTAGENIC DATA (RTECS);
REPRODUCTIVE EFFECTS DATA (RTECS).
CARCINOGEN STATUS: HUMAN INADEQUATE EVIDENCE (IARC GROUP-3 FOR ANAESTHETICS,
VOLATILE); ANIMAL INADEQUATE EVIDENCE (IARC).
ACUTE TOXICITY LEVEL: INSUFFICIENT DATA.
TARGET EFFECTS: SIMPLE ASPHYXIANT; CENTRAL NERVOUS SYSTEM DEPRESSANT.
POISONING MAY ALSO AFFECT THE BLOOD, LIVER, AND KIDNEYS.
ADDITIONAL DATA: CENTRAL NERVOUS SYSTEM DEPRESSANTS MAY ENHANCE THE TOXIC
EFFECTS.
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HEALTH EFFECTS AND FIRST AID
INHALATION:
NITROUS OXIDE:
SIMPLE ASPHYXIANT/NARCOTIC.
ACUTE EXPOSURE- INHALATION OF HIGH CONCENTRATIONS WITHOUT ADEQUATE OXYGEN
CAN RESULT IN HEADACHE AND SERIOUS ANOXIA CAUSING FATAL CARDIAC
ARRHYTHMIAS OR BRAIN DAMAGE WITH CEREBRAL EDEMA, PERMANENT MENTAL DEFICIT,
AND VISUAL SYSTEM INVOLVEMENT. HIGH CONCENTRATIONS MIXED WITH AIR OR
OXYGEN MAY PRODUCE SIGNS OF CENTRAL NERVOUS SYSTEM DEPRESSION INCLUDING
DROWSINESS, LIGHTHEADEDNESS, CONFUSION, HYSTERIA, ANESTHESIA, AND
UNCONSCIOUSNESS. SOME PERSONS MAY EXPERIENCE NAUSEA, AND OCCASIONALLY
VOMITING, FOLLOWING ANESTHESIA. ANESTHETIC CONCENTRATIONS MAY PRODUCE
PERMANENT HEARING LOSS IN PERSONS WHO HAVE HAD MIDDLE EAR SURGERY.
EXPOSURE OF PREGNANT RATS TO 75% NITROUS OXIDE FOR 8 HOURS ON THE 15TH DAY
OF GESTATION RESULTED IN PERMANENT ALTERATIONS IN NEUROBEHAVIORAL OUTPUT
OF THE NEWBORNS AS EXHIBITED BY HYPERACTIVITY IN MALES AND HYPOACTIVITY IN
FEMALES.
CHRONIC EXPOSURE- PROLONGED OCCUPATIONAL EXPOSURE OR ABUSE HAS RESULTED IN
NEUROLOGIC EFFECTS INCLUDING INITIAL SIGNS OF NUMBNESS, PARESTHESIAS,
AND LOSS OF PAIN AND TEMPERATURE SENSATION, PROGRESSING TO MUSCLE
WEAKNESS, LOSS OF BALANCE, GAIT ATAXIA, LHERMITTE'S SIGN, IMPOTENCE,
SPHINCTER DIFFICULTIES, LOSS OF BLADDER AND VAGINAL SENSATION, AND
REDUCTION IN DEXTERITY, COGNITION, AND MOTOR AND AUDIOVISUAL SKILLS.
OHS16790 PAGE 004 OF 007
RECOVERY MAY OCCUR IN MONTHS, BUT DAMAGE MAY BE PERMANENT. SIGNS OF
BONE MARROW DEPRESSION INCLUDING FATAL APLASTIC ANEMIA HAVE BEEN REPORTED.
THERE HAVE ALSO BEEN INCREASED INCIDENCES OF KIDNEY AND LIVER DISORDERS,
SPONTANEOUS ABORTIONS, AND FETAL MALFORMATIONS REPORTED AMONG DENTISTS
AND THEIR ASSISTANTS. EXPOSURE TO NITROUS OXIDE IN UTERO PRIOR TO
ORGANOGENESIS RESULTED IN PHYSICAL MALFORMATIONS IN RAT FETUSES; PERMANENT
ALTERATIONS IN BRAIN FUNCTION CAN RESULT FOLLOWING EXPOSURE DURING A
PERIOD BEYOND MAJOR ORGANOGENESIS. PROLONGED EXPOSURE PRODUCED SOME
DAMAGE TO CHROMOSOMES IN BONE MARROW CELLS AND SPERMATOGONIAL CELLS IN
MALE RATS. 500 PPM 8 HRS/DAY/35 DAYS DISRUPTED HORMONAL CYCLES AND
DECREASED CONCEPTION IN FEMALE RATS.
FIRST AID- REMOVE FROM EXPOSURE AREA TO FRESH AIR IMMEDIATELY. IF BREATHING
HAS STOPPED, GIVE ARTIFICIAL RESPIRATION. MAINTAIN AIRWAY AND BLOOD
PRESSURE AND ADMINISTER OXYGEN IF AVAILABLE. KEEP AFFECTED PERSON WARM AND
AT REST. TREAT SYMPTOMATICALLY AND SUPPORTIVELY. ADMINISTRATION OF OXYGEN
SHOULD BE PERFORMED BY QUALIFIED PERSONNEL. GET MEDICAL ATTENTION
IMMEDIATELY.
SKIN CONTACT:
NITROUS OXIDE:
ACUTE EXPOSURE- NO ADVERSE EFFECTS HAVE BEEN REPORTED FROM THE GAS. DUE TO
RAPID EVAPORATION, THE LIQUID MAY CAUSE FROSTBITE WITH REDNESS, TINGLING,
AND PAIN OR NUMBNESS. IN MORE SEVERE CASES, THE SKIN MAY BECOME HARD
AND WHITE AND BLISTERS MAY FORM.
CHRONIC EXPOSURE- NO DATA AVAILABLE.
FIRST AID- IT IS UNLIKELY THAT EMERGENCY TREATMENT WILL BE REQUIRED. IF
ADVERSE EFFECTS OCCUR, GET MEDICAL ATTENTION.
IN CASE OF FROSTBITE, WARM AFFECTED SKIN IN WARM WATER AT A TEMPERATURE OF
107 F. IF WARM WATER IS NOT AVAILABLE OR IMPRACTICAL TO USE, GENTLY WRAP
AFFECTED PART IN BLANKETS. ENCOURAGE VICTIM TO EXERCISE AFFECTED PART WHILE
IT IS BEING WARMED. ALLOW CIRCULATION TO RETURN NATURALLY (MATHESON GAS,
6TH ED.). GET MEDICAL ATTENTION IMMEDIATELY.
EYE CONTACT:
NITROUS OXIDE:
ACUTE EXPOSURE- NO ADVERSE EFFECTS HAVE BEEN REPORTED FROM THE GAS. DUE TO
RAPID EVAPORATION, THE LIQUID MAY CAUSE FROSTBITE WITH REDNESS, PAIN, AND
BLURRED VISION.
CHRONIC EXPOSURE- NO DATA AVAILABLE.
FIRST AID- IT IS UNLIKELY THAT CONTACT WITH THE GAS FORM WILL REQUIRE
EMERGENCY TREATMENT. IF CONTACT WITH LIQUEFIED OR COMPRESSED GAS OCCURS,
WASH WITH LARGE AMOUNTS OF WARM WATER UNTIL NO EVIDENCE OF CHEMICAL REMAINS
(APPROXIMATELY 15-20 MINUTES). GET MEDICAL ATTENTION IMMEDIATELY.
INGESTION:
NITROUS OXIDE:
ACUTE EXPOSURE- IF THE LIQUID IS SWALLOWED, FROSTBITE DAMAGE OF THE LIPS,
MOUTH, AND MUCOUS MEMBRANES MAY OCCUR.
CHRONIC EXPOSURE- NO DATA AVAILABLE.
FIRST AID- IT IS UNLIKELY THAT EMERGENCY TREATMENT WILL BE REQUIRED.
IF ADVERSE EFFECTS OCCUR, TREAT SYMPTOMATICALLY AND SUPPORTIVELY AND
GET MEDICAL ATTENTION.
OHS16790 PAGE 005 OF 007
ANTIDOTE:
NO SPECIFIC ANTIDOTE. TREAT SYMPTOMATICALLY AND SUPPORTIVELY.
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REACTIVITY
REACTIVITY:
STABLE UNDER NORMAL TEMPERATURES AND PRESSURES. AT TEMPERATURES GREATER THAN
300 C, MAY DECOMPOSE AND ACT AS AN OXIDIZER.
INCOMPATIBILITIES:
NITROUS OXIDE:
ACETYLENE: FORMS EXPLOSIVE MIXTURE.
ALUMINUM: OXIDIZES.
AMMONIA: FORMS EXPLOSIVE MIXTURE.
BORON (AMORPHOUS): IGNITES WHEN HEATED.
CADMIUM: OXIDIZES @ 300 C.
CARBON MONOXIDE: EXPLOSION HAZARD.
COBALT: OXIDIZES @ 200 C.
COPPER: OXIDIZES @ 150 C.
DITUNGSTEN CARBIDE: INCANDESCENT REACTION.
ETHANOL: MIXTURES WITH SUPERCRITICAL NITROUS OXIDE MAY DETONATE.
HYDRAZINE: IGNITES.
HYDROGEN: FORMS EXPLOSIVE MIXTURE.
HYDROGEN + OXYGEN: IGNITION REACTION WITH POSSIBLE EXPLOSION.
HYDROGEN SULFIDE: FORMS EXPLOSIVE MIXTURE.
IRON: OXIDIZES @ 170 C.
LEAD: OXIDIZES @ 300 C.
LITHIUM HYDRIDE: IGNITES.
METHANOL: MIXTURES WITH SUPERCRITICAL NITROUS OXIDE MAY DETONATE.
NICKEL: OXIDIZES @ 200 C.
OXIDIZABLE ORGANIC MATERIALS: MIXTURES WITH SUPERCRITICAL NITROUS OXIDE MAY
DETONATE.
ORGANIC PEROXIDES: INCOMPATABLE.
PHENYLLITHIUM: FORMS UNSTABLE PRODUCTS.
PHOSPHINE: EXPLODES WHEN SPARKED.
REDUCING AGENTS (STRONG): VIOLENT REACTION @ ROOM TEMPERATURE.
SODIUM (GASEOUS): INCANDESCES @ 260 C.
STANNOUS CHLORIDE: VIOLENT REACTION.
TIN (II) OXIDE: IGNITES @ 400 C.
TUNGSTEN CARBIDE: IGNITES WITH INCANDESCENCE @ 600 C.
DECOMPOSITION:
THERMAL DECOMPOSITION PRODUCTS MAY INCLUDE TOXIC OXIDES OF NITROGEN.
POLYMERIZATION:
HAZARDOUS POLYMERIZATION HAS NOT BEEN REPORTED TO OCCUR UNDER NORMAL
TEMPERATURES AND PRESSURES.
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STORAGE AND DISPOSAL
OBSERVE ALL FEDERAL, STATE AND LOCAL REGULATIONS WHEN STORING OR DISPOSING
OF THIS SUBSTANCE. FOR ASSISTANCE, CONTACT THE DISTRICT DIRECTOR OF THE
ENVIRONMENTAL PROTECTION AGENCY.
OHS16790 PAGE 006 OF 007
**STORAGE**
STORE IN ACCORDANCE WITH 29 CFR 1910.105.
STORE AWAY FROM INCOMPATIBLE SUBSTANCES.
CONSULT NFPA PUBLICATION 43C, STORAGE OF GASEOUS OXIDIZING MATERIALS, FOR
STORAGE REQUIREMENTS.
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CONDITIONS TO AVOID
AVOID CONTACT WITH COMBUSTIBLE MATERIALS (WOOD, PAPER, FUEL, OILS, ETC);
CONTACT MAY RESULT IN IGNITION OR EXPLOSION. DO NOT PERMIT DAMAGE OR
OVERHEATING OF CONTAINERS. CONTENTS ARE UNDER PRESSURE; CONTAINERS MAY
VIOLENTLY RUPTURE AND TRAVEL A CONSIDERABLE DISTANCE.
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SPILL AND LEAK PROCEDURES
OCCUPATIONAL SPILL:
KEEP COMBUSTIBLES (WOOD, PAPER, OIL, ETC.) AWAY FROM SPILLED MATERIAL. STOP
LEAD IF YOU CAN DO IT WITHOUT RISK. ISOLATE AREA UNTIL GAS HAS DISPERSED. KEEP
UNNECESSARY PEOPLE AWAY; ISOLATE HAZARD AREA AND DENY ENTRY. STAY UPWIND, OUT
OF LOW AREAS, AND VENTILATE CLOSED SPACES BEFORE ENTERING.
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PROTECTIVE EQUIPMENT
VENTILATION:
PROVIDE LOCAL EXHAUST VENTILATION SYSTEM TO MEET PUBLISHED EXPOSURE LIMITS.
RESPIRATOR:
THE FOLLOWING RESPIRATORS ARE RECOMMENDED BASED ON INFORMATION FOUND IN THE
PHYSICAL DATA, TOXICITY AND HEALTH EFFECTS SECTIONS. THEY ARE RANKED IN
ORDER FROM MINIMUM TO MAXIMUM RESPIRATORY PROTECTION.
THE SPECIFIC RESPIRATOR SELECTED MUST BE BASED ON CONTAMINATION LEVELS FOUND
IN THE WORK PLACE, MUST BE BASED ON THE SPECIFIC OPERATION, MUST NOT EXCEED
THE WORKING LIMITS OF THE RESPIRATOR AND MUST BE JOINTLY APPROVED BY THE
NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH AND THE MINE SAFETY
AND HEALTH ADMINISTRATION (NIOSH-MSHA).
ANY TYPE 'C' SUPPLIED-AIR RESPIRATOR WITH A FULL FACEPIECE OPERATED IN
PRESSURE-DEMAND OR OTHER POSITIVE PRESSURE MODE OR WITH A FULL FACEPIECE,
HELMET OR HOOD OPERATED IN CONTINUOUS-FLOW MODE.
ANY SELF-CONTAINED BREATHING APPARATUS WITH A FULL FACEPIECE OPERATED IN
PRESSURE-DEMAND OR OTHER POSITIVE PRESSURE MODE.
FOR FIREFIGHTING AND OTHER IMMEDIATELY DANGEROUS TO LIFE OR HEALTH CONDITIONS:
ANY SELF-CONTAINED BREATHING APPARATUS THAT HAS A FULL FACEPIECE AND IS
OPERATED IN A PRESSURE-DEMAND OR OTHER POSITIVE-PRESSURE MODE.
ANY SUPPLIED-AIR RESPIRATOR THAT HAS A FULL FACEPIECE AND IS OPERATED IN A
PRESSURE-DEMAND OR OTHER POSITIVE-PRESSURE MODE IN COMBINATION WITH AN
AUXILIARY SELF-CONTAINED BREATHING APPARATUS OPERATED IN PRESSURE-DEMAND
OHS16790 PAGE 007 OF 007
OR OTHER POSITIVE-PRESSURE MODE.
CLOTHING:
FOR THE GAS FORM, PROTECTIVE CLOTHING NOT REQUIRED.
IF CONTACT WITH THE LIQUID FORM IS POSSIBLE, EMPLOYEE MUST WEAR APPROPRIATE
PROTECTIVE CLOTHING AND EQUIPMENT TO PREVENT SKIN FROM FREEZING.
GLOVES:
WEAR FULL PROTECTIVE, COLD INSULATING GLOVES.
EYE PROTECTION:
FOR THE GAS FORM EYE PROTECTION IS NOT REQUIRED BUT RECOMMENDED.
WHERE THERE IS ANY POSSIBILITY OF CONTACT WITH THE LIQUID FORM, EMPLOYEE MUST
WEAR SPLASH-PROOF SAFETY GOGGLES AND A FACESHIELD TO PREVENT CONTACT WITH THIS
SUBSTANCE. CONTACT LENSES SHOULD NOT BE WORN.
EMERGENCY WASH FACILITIES:
WHERE THERE IS ANY POSSIBILITY THAT AN EMPLOYEE'S EYES AND/OR SKIN MAY BE
EXPOSED TO THE LIQUID FORM OF THIS SUBSTANCE, THE EMPLOYER SHOULD PROVIDE AN
EYE WASH FOUNTAIN AND QUICK DRENCH SHOWER WITHIN THE IMMEDIATE WORK AREA FOR
EMERGENCY USE.
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COPYRIGHT 1992 OCCUPATIONAL HEALTH SERVICES, INC.. ALL RIGHTS RESERVED.
CREATION DATE: 07/15/86 REVISION DATE: 09/11/92
--
To you -- Is it movement or is it action? Is it contact or just
reaction? And you -- Revolution or just resistance? Is it living
or just existence? -N. Peart