Newsgroups: alt.drugs
Subject: Re: Pets and Drugs

[S--E] at [PHYSICS.watstar.uwaterloo.ca] (Mark Shoesmith) writes:
>[an 24925] at [anon.penet.fi] (Nickname: Rico) writes:
>>From: [an 24925] at [anon.penet.fi] (Nickname: Rico)
>>Date: Fri,  6 Aug 1993 04:51:38 UTC
>>Subject: Pets and Drugs
>>
>>I was wondering if there is any information of getting dogs and cats
>>stoned.  Is it really bad for them?  I would also like to here a few
>>personal experiences, I'm sure there are some good ones out there.
>>
>
>First aid books for dogs and cats say that pot is poisonous for both species.
>I don't know how much constitutes a lethal dose though, but I'd be wary of 
>feeding your stash to your pet.

According to "Marihuana: An Annotated Bibliography", here's the two main
refs for marihuana toxicity in dogs:

869. Durandina, A.I.; and Romasenko, V.A.,
     Bull. Narcotics, 24 (10), 31-37 (1972).

     Functional and dMorphological Disorders
     in Chronic Poisoning by Resinous Sub-
     stances Prepared from Yujnochuisk Can-
     nabis Resin. (Part 2).

     A detailed description of the pathology
     of chronic, fatal poisoning by Cannabis
     resin in dogs. Symptoms point to damage
     of the vegetative centers of the brain as
     well as areas concerned with coordination
     and affect. Lack of acute effects of resin
     after the first few oses and intermittant
     nature of some symptoms, for example
     periods of prostration, suggest processes
     of compensation and adaptation, which
     are overcome by progressive neurological
     damage.

2804. Thompson, G.R.; Rosenkrantz, H.;
      Schaeppi, U.H.; and Braude, M.C.,
      Toxicol. Appl. Pharmacol., 25,
      363-72 (1973).

      Comparison of Acute Oral Toxicity of
      Cannabinoids in Rats, Dogs and Monkeys.

      Delta9-THC, Delta8-THC and Cannabis extract
      were given p.o. to rats, dogs, and mon-
      keys as solutions to absolute EtOH,
      sesame oil, or sesame oil and 2.5-9.0%
      EtOH. Large doses were administered to
      as to establish minimum lethal oral dose
      in each species and produce maximal
      biological effects. The oral adminisation [sic]
      of cannabinoids to rats, dogs, and mon-
      keys consistently produced depression
      manifested as inactivity, drowsiness, and
      lack of coordination of species--specific
      reactions observed.


If anyone goes to the actual trouble of looking these up, please
summarize to the net!

The bibliography only covers studies from 1964 to 1974 (the Library of
Congress is off-line, but Melvyl shows an 80, 81, and 83-84 supplement
available). There are quite a few more studies *involving* cats and
dogs, but these are the only ones I found dealing specifically with
lethality.

Jerry Stratton
[j--r--y] at [teetot.acusd.edu]
------
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