From: [n--bo--y] at [REPLAY.COM] (Anonymous) Newsgroups: alt.drugs.chemistry Subject: ADC2:the Guy under the Bridge(POPi) Date: 5 Mar 1996 02:23:55 +0100 REPLY TO: <[an 455616] at [anon.penet.fi]> ........................................................................... Who is that ugly guy under the bridge, and why does he ask such wierd questions? ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ In our last segment, we identified some of the pollutants or more specifically, CRAP that we might find in our alleged Methamphetamine and touched on the effects they might have upon injestion, but that was nothing really, it does not touch on the real meat of your inquiry as to why the different types of highs or high substitutes. Any glorp could have figured that shit out, given time. I mean, really. Having shot-up perhaps a gallon of Acetone over the years, one would hope that he could finally link the taste to the smell to the cross-eyed wooziness at some point. Despite the damage done by the drug-solvent combinations, it's a simple Watsonian type of learning response, eh? Not all that impressive. But there is much more to it, it gets pretty complicated, perhaps even what we sometimes refer to as `highFalootin', it is propitious that I, Dr. Thaddius POPeye, have just the right educayshunal background, calibrated-scientific degrees, as well as the necessary interactive flexvoCabulary to explain these things in such a way that they may be understood by someone who still has plenty of brain cells. To begin with, we need some notion of just how psychoactive drugs work. To understand that, we need a fully comprehensive, total understanding of the human Central Nervous System... No problem, it's actually VERY simple and I think I can cover what is now known, as well as a few things the science guys haven't quite grasped , in a few paragraphs. It's a system which utilizes both electrical and chemical activity, or what we call in hyphenated-grammatical science, electro-chemical. The electrical part is made up of nerve cells and they are just wires that conduct electricity. Drugs don't react with this part. Things that have an effect on this part of the system would be like meat cleavers, bullets, and external electrical feeds... and perhaps very powerful magnetic fields. This is why those guys who put powerful magnets under their hats are so goofy. The nerve cells are strung together with synapses, the chemical part (see fig 1) each synapse is a miniature chemical system...as the signal passes through the synapse it becomes vulnerable to amplification, distortion, elimination, colorization, etc. by other chemicals which have been introduced into the larger system by trauma, fatigue, excitation, or design. This is the place where the drugs do their thing. The synapses are made up of receptor sites and..... ummmmmmmmm... jumperthings. The jumperthings are essentially just plain old chemical compounds with hard-to-remember names. fig.1 A diagram of the CNS ~ ~ O O v Q W _|_ 0 black lines = nerve cells \ / | \ O white spaces = synapses \/ | \ | \ | \ / \ M / \ / \ | \ | \ _| \_ When Dr.POPeye was at University, before all these computers and ball point pens, there were only 4 types of synaptic chemical jumperthings. Since then, there may have been advances in the field of neurology and there could be more now, the human body quickly adapts to scientific progress and will evolve physical characteristics in a very short time in order to resolve any such inconsistencies and remain current with contemporary anatomical dogma. Lets see if I can remember the elements of the old standard four-banger synaptic receptor-chemical configuration. 1. Seradrenacholadopanin 2.......uhhhhhhh 3. lemme think 4. mmmmmmmmm... I sorta forget the other ones, but the names are not that important, and there's only a few things to know really. The receptors are little locks and the chemical jumperthings are little keys. If you know about how taste buds work, that's it. You got it. And then there's things in there, or that you can put in there, that work for or against the chemical jumperthings. One would be like Lock-Ease, and the other like rust, and sometimes like breaking the key off in the lock or Nutra Sweet... well, you get the idea, anyway. The resultant terminology is logical enough, fr'instance, let's say we're dealing with the religious portion of the brain. And let's say #3 chemical jumper which I can't remember, is referred to as a Chrystal jumperthing. So it's like when you're having a dream about being in a cartoon, and there's a devil guy on one shoulder and an angel guy on the other. Okay, lets say those shoulder guys are drugs, the angel guy would be a Chrystian drug, or Chryst enhancer, the devil guy would be a Chryst inhibitor or anti-Chryst. And then there's some more lingo about synaptic imposters that look and act like jumperthings, so all of a sudden you have a shitLoad of them in there, or what we call a rich mixture in carbeuration theory which tends to make things happen faster or more often, and result in what we might think of as `spun', or `fuckin' zoomin', man', not unlike the lock-ease effect which can cause run-on sentences. Other synaptic poseurs can look like jumperthings and fit the locks but don't do anything, they just block the signal from the genuine jumperthings which comes in handy if the genuine jumperthing is trying to convey some signal like PAIN or YogiSpam. This model eventually leads to an endless stream of related vocabulary and hyphenated-grammatical terminology like uptake, re-uptake, dan-blockers, uptake re-inhibitor, etc. etc. but all that stuff is just common sense. And that's all there is to it. Beyond the Western Scientific constricts of analysis, we refer to this model as a particle model. It fits some of the observable data and much of the limited pinkBoy causal worldView, but falls short of explaining the more interesting effects of drugExcursion, or even some things as simple as how aspirin works. For these discussions we would have to explore the Wave Model of CNS activity, which incorporates the electrical parts of the system and wierd NewAgeType aural traditions, or the Unified Field Theory which integrates the entire universe as an extension of the system... but you either already know what I'm talking about, or you're confused, perhaps incredulous... At this point in time, there has been no crossing back and forth across THAT line and nothing I can say or do will change that. But Full-on cranking is, for the most part, just a faster, hornier, desperate and twisted run accross the more familiar dimensional landscape, and this primitive model will do just fine for our purposes. -POPeye cont. on