From: [d--e] at [unislc.slc.unisys.com] (Dale Clark)
Subject: STP
Date: Mon, 14 Jun 1993 14:58:23 -0600 (MDT)


		     ----------------------------------
                                S.T.P. (D.O.M.)
                     ----------------------------------


GENERAL INFO
------------
DOM (STP): 2,5-Dimethoxy-4-Methylamphetamine.  Added carbon to
the chain to alter phenethylamine 2C-D into the amphetamine DOM.
Replacement of the Br atom in DOB with a methyl group would also
produce DOM.  Chemical cousin of mescaline, but more toxic.

 
STRUCTURE
---------

                       CH3O   -----   -----    NH2 
                           \ /    \\ /     \ /  
                            ||      |       |
                           / \    // \      |
                        H3C   -----   OCH3  CH2
         

LD-50
-----
No citations are available regarding the LD-50 of STP.
       

ACTIONS
------- 
STP has a potency of about 3-10mg and a duration of 14-20 hours. 
First synthesized by Shulgin, and is what he calls his "Problem 
Child" (in reference to Albert Hofmann's name for LSD).  It 
gained considerable use in the 1960's and people taking 30mg+ 
(a whopping dose) had some very dissasociative, bad trips.  
It was known as STP, which stands for the motor oil additive 
actually, but was also known as "Serenity, Tranquility and Peace."
>From descriptions it seems LSD-like, with possibly even more of 
a head-trip, and more physical effects.  5-10mg seems *much* 
more appropriate from the descriptions with very good effects.  
Only at higher (20-30mg) doses does it appear to cause unpleasant 
side-effects.  Bad trips are not uncommon on this drug.

An overdose of STP can be fatal, and there is the real danger a
STP-induced psychosis can last for years.  Flashbacks occur
frequently.  DOB is derived from DOM and is easy to produce.
Although only one-tenth as strong as LSD, it is often sold as
being that drug, exposing users to DOM-type dangers.  


DRUG INTERACTIONS
-----------------
Chlorpromazine may aggravate unpleasant psychological
symptoms.


CREATION PROCESS
----------------
STP is produced by refluxing 2,5-dimethoxytoluene with 2,5-
dimethoxy-4- methylbenzaldehyde and phosphorous oxychloride.  The 
2,5-dimethoxytoluene is then distilled off, leaving the final
product behind.  The entire procedure requires 2 to 3 days
for completion.

CHEMICAL			COMMERCIAL USE / HAZARDS
--------			------------------------
2,5-dimethoxy-4-methyl-		Organic preparations.
 benzaldehyde			IRRITANT

2,5-dimethoxytoluene		Organic preparations.
				IRRITANT

dimethylformamide		Solvent for vinyl resins, organic
				preparations, orlon synthesis.
				TOXIC / FLAMMABLE

N-methylformanilide		Organic synthesis.
				IRRITANT

Phosphorous oxychloride		Gasoline additive, organic synthesis,
				fire retardant, plastics.
				CORROSIVE / TOXIC / IRRITANT